Our poorly ventilated homes and buildings are making us stupid, sick, and tired—at a cost that is staggering. Improvement of today’s ventilation standards can increase human productivity with a value that is more than 100 times the associated cost of increased ventilation. Thus, a new home-design paradigm that places human health, well-being, and productivity is desperately needed. This session examines the impact of IAQ on our health and productivity, and defines a new set of IAQ metrics. These metrics translate basic indoor air quality measurements of carbon dioxide and TVOC (Total Volatile Organic Compounds) into metrics related to human performance. The results of comparing homes without smart ventilation and homes with smart ventilation control using these new metrics are included.